Hjärnfondens (The Swedish Brain Foundation’s) Alzheimer Symposium
Welcome to a symposium about decoding molecular pathways and biomarkers for future therapies for Alzheimer’s disease!
The symposium will feature expert-led sessions, keynote lecture and in-depth discussions on novel biomarkers, neuroimaging, and drug development. Network with leading scientists and explore the latest breakthroughs in Alzheimer research. Register here!Program
| 8:15–9:00 |
Registration |
| 9:15–9:20 |
Introduction and welcome to the symposiumProfessor Cecilia Lundberg, Lund University Chair of the Swedish Brain Foundation’s scientific committee |
| 9:20–10:05 |
Keynote lecture: Alzheimer’s disease: From molecular pathways to clinical hallmarksProfessor Bart De Strooper, VIB-KU Leuven Center for Brain & Disease Research, Belgium; UK Dementia Research Institute, University College London, UK |
| 10:05–11:50 |
SESSION I: The role of brain vasculature and amyloid fibril polymorphism in Alzheimer’s disease progressionChairs: Christer Betsholtz (KI) and Per Hammarström (LiU)
10:05–10:25
What role does the blood-brain barrier play in Alzheimer’s disease?Professor Christer Betsholtz, Karolinska Institute |
| 10:25–10:50 |
Coffee and mingle
10:50–11:30
The potential for amyloid-beta transmission: What the evidence tells usAssociate Professor and Honorary Consultant Neuropathologist, Zane Jaunmuktane, University College London Hospitals
11:30–11:50
The role of fibril polymorphism of experimentally transmissible Aβ-amyloid seedsProfessor Per Hammarström, Linköping University |
| 11:50–13:00 |
Lunch |
| 13:00–14:20 |
SESSION II: Novel Alzheimer’s biomarkers and mechanistic insights into disease progressionChairs: Kaj Blennow (GU) and Martin Hallbeck (LiU)
13:00–13:20
Aβ and tau AD biomarkers in CSF and blood – What do and don’t tell us about brain pathophysiologyProfessor Kaj Blennow, Gothenburg University
13:20–13:40
Tau is tethered within EVs: Insights into the genesis of secreted tau species in human brainPhD Steph Fowler, University of Oxford
13:40–14:00
The role of autophagy in Alzheimer’s disease – Potential for treatmentAssociate Professor Per Nilsson, Karolinska Institute
14:00–14:20
From endosomes to vesicles: Cellular pathways driving Alzheimer’s diseaseProfessor Martin Hallbeck, Linköping University |
| 14:20–15:00 |
Coffee and mingle |
| 15:00–16:20 |
SESSION III: Neuroimaging and drug development: Advancing novel treatment approaches for Alzheimer’s diseaseChairs: Stina Syvänen (UU) and Janne Johansson (KI)
15:00–15:40
TBDProfessor Tuomas Knowles, University of Cambridge
15:40–16:00
Prevention of amyloid-associated neurotoxicity by the BRICHOS domain – Molecular mechanisms and therapeutic potentialProfessor Janne Johansson, Karolinska Institute
16:00–16:20
Bispecific antibody formats for neuroimaging and therapeuticsProfessor Stina Syvänen, Uppsala University |
| 16:20–16:40 |
Panel discussionModerator: Professor Cecilia Lundberg, Lund University |
| 16:40–16:45 |
Concluding remarks |
Event details
9 April 2025
08.15 - 06.15